# Somatic Recombination # Somatic Recombination Somatic recombination refers to the altering of genetic sequences within somatic (body) cells that will not be passed on to future offspring. The most prevalent use of this process within organisms is often [[Anki Flashcards/Courses/Molecular Biology II/Chapter 17 - The Genetic Code|the immune system]] which needs to generate a large diversity of **Somatic Recombination** occurs in both [[T-Cells]] **AND** [[B Cells]] Variable Diversity Joining Only Developing: RAG I & RAG II Tdt ### Immunoglobulin Recombination > See also: > - [[Antibodies]] #### Chromosomal Arrangement of Ig Genes ![[Ig Heavy and Light Chain Loci.png|400]] ### T-Cell Receptor Recombination > See also: > - [[T-Cell Receptors (TCRs)]] ### Somatic Hypermutation Activation-induced cytidine deaminase (AID)  ## Somatic Hypermutation Activation-induced cytidine deaminase (AID)