> See also: > - [[Transcriptional Regulation]] # Transcription ## Major Stages 1. Initiation 2. Elongation 3. Termination ### Initiation >basically our version of [[Operons|operons]] found in prokaryotes (pathways yo) ![[Transcription Initiation Complex.png|300]] The **promoter** region of a DNA strand indicates where the RNA polymerase needs to bind to so that transcription can occur. The non-template DNA strand is in the 5' -> 3' direction while the template is being read in the 3' to 5' direction. Protein **transcription factors** group together at the promoter region and acts as an indicator for the RNA polymerase to bind. ### Elongation RNA is extended by addition of new nucleotides to the free 3' hydroxyl of the growing strand ### Termination The methods of termination differs between prokaryotes and eukaryotes ## Post-Transcriptional Modifications The **poly-A tail** is added to the mRNA to protect it from other enzymes trying to consume it as it travels in the cytoplasm ## The Transcriptome > See also: > - [[Transcriptional Regulation]]